Gene: Ptgs2 (prostaglandin-endoperoxide synthase 2) Rattus norvegicus
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Symbol: Ptgs2
Name: prostaglandin-endoperoxide synthase 2
Description: Exhibits oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen; involved in several processes, including animal organ development, modulation of chemical synaptic transmission, and positive regulation of cytokine production; localizes to the cytoplasm and protein-containing complex; colocalizes with the caveola; used to study several diseases, including Barrett's esophagus, artery disease (multiple), brain disease (multiple), lung disease (multiple), and neurodegenerative disease (multiple); biomarker of several diseases, including asthma, astrocytoma (multiple), brain ischemia, carcinoma (multiple), and inflammatory bowel disease (multiple); orthologous to human PTGS2 (prostaglandin-endoperoxide synthase 2); PARTICIPATES IN acetylsalicylic acid pharmacodynamics pathway; antipyrine drug pathway; arachidonic acid metabolic pathway; INTERACTS WITH (+)-alpha-tocopherol; (+)-pilocarpine; (-)-epigallocatechin 3-gallate.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: COX-2; Cox2; cyclooxygenase 2; cyclooxygenase-2; PGH synthase 2; PGHS-2; PHS II; prostaglandin G/H synthase 2; prostaglandin H2 synthase 2
Orthologs:
Homo sapiens (human) : PTGS2 (prostaglandin-endoperoxide synthase 2)  HGNC  Alliance
Mus musculus (house mouse) : Ptgs2 (prostaglandin-endoperoxide synthase 2)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ptgs2 (prostaglandin-endoperoxide synthase 2)
Pan paniscus (bonobo/pygmy chimpanzee) : PTGS2 (prostaglandin-endoperoxide synthase 2)
Canis lupus familiaris (dog) : PTGS2 (prostaglandin-endoperoxide synthase 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ptgs2 (prostaglandin-endoperoxide synthase 2)
Sus scrofa (pig) : PTGS2 (prostaglandin-endoperoxide synthase 2)
more info ...
Allele / Splice: Ptgs2em1Mcwi   Ptgs2em2Mcwi  
Genetic Models: SS-Ptgs2em1Mcwi SS-Ptgs2em2Mcwi
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01367,351,230 - 67,356,920 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01372,315,959 - 72,324,483 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41364,427,288 - 64,432,978 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11364,441,245 - 64,449,480 (+)NCBI
Celera1362,129,439 - 62,135,131 (+)NCBICelera
Cytogenetic Map13q21NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model