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Gene: Gsk3a (glycogen synthase kinase 3 alpha) Rattus norvegicus
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Symbol: Gsk3a
Name: glycogen synthase kinase 3 alpha
Description: Exhibits protein kinase A catalytic subunit binding activity and protein serine/threonine kinase activity. Involved in several processes, including aging; negative regulation of dendrite development; and positive regulation of neuron apoptotic process. Localizes to the cytoplasm and microtubule. Human ortholog(s) of this gene implicated in amyotrophic lateral sclerosis. Orthologous to human GSK3A (glycogen synthase kinase 3 alpha); PARTICIPATES IN glycogen biosynthetic pathway; nuclear factor, erythroid 2 like 2 signaling pathway; phosphatidylinositol 3-kinase-Akt signaling pathway; INTERACTS WITH (RS)-amphetamine; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: FA; factor A; glycogen synthase kinase-3 alpha; GSK-3 alpha; serine/threonine-protein kinase GSK3A
Orthologs:
Homo sapiens (human) : GSK3A (glycogen synthase kinase 3 alpha)  HGNC  Alliance
Mus musculus (house mouse) : Gsk3a (glycogen synthase kinase 3 alpha)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Gsk3a (glycogen synthase kinase 3 alpha)
Pan paniscus (bonobo/pygmy chimpanzee) : GSK3A (glycogen synthase kinase 3 alpha)
Canis lupus familiaris (dog) : GSK3A (glycogen synthase kinase 3 alpha)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Gsk3a (glycogen synthase kinase 3 alpha)
Sus scrofa (pig) : GSK3A (glycogen synthase kinase 3 alpha)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: suggests misassembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0182,097,244 - 82,108,238 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0183,365,717 - 83,374,707 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4180,505,517 - 80,514,139 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1180,583,627 - 80,592,250 (-)NCBI
Celera175,259,483 - 75,269,362 (-)NCBICelera
Cytogenetic Map1q21NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Gsk3a
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 620351
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.