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Gene: Arc (activity-regulated cytoskeleton-associated protein) Rattus norvegicus
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Symbol: Arc
Name: activity-regulated cytoskeleton-associated protein
CRRD ID: 62037
Description: Exhibits mRNA binding activity. Involved in several processes, including learning or memory; positive regulation of AMPA receptor activity; and regulation of synaptic plasticity. Localizes to several cellular components, including glutamatergic synapse; postsynaptic density membrane; and postsynaptic endosome. Biomarker of middle cerebral artery infarction and visual epilepsy. Orthologous to human ARC (activity regulated cytoskeleton associated protein); INTERACTS WITH (25R)-cholest-5-ene-3beta,26-diol; (S)-amphetamine; 1,2,4-trimethylbenzene.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: activity regulated cytoskeletal-associated protein; activity-regulated gene 3.1 protein; ARC/ARG3.1; arg3.1; rg3.1
Orthologs:
Homo sapiens (human) : ARC (activity regulated cytoskeleton associated protein)  HGNC  Alliance
Mus musculus (house mouse) : Arc (activity regulated cytoskeletal-associated protein)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Arc (activity regulated cytoskeleton associated protein)
Pan paniscus (bonobo/pygmy chimpanzee) : ARC (activity regulated cytoskeleton associated protein)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Arc (activity regulated cytoskeleton associated protein)
Sus scrofa (pig) : ARC (activity regulated cytoskeleton associated protein)
Chlorocebus sabaeus (African green monkey) : ARC (activity regulated cytoskeleton associated protein)
Heterocephalus glaber (naked mole-rat) : Arc (activity regulated cytoskeleton associated protein)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.07115,907,097 - 115,911,059 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl7115,907,097 - 115,910,541 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.07115,812,499 - 115,815,958 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.47112,771,937 - 112,775,381 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.17112,806,166 - 112,809,611 (-)NCBI
Celera7102,957,256 - 102,960,700 (-)NCBICelera
Cytogenetic Map7q34NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Candidate Gene Status
Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Arc
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 62037
Created: 2001-04-11
Species: Rattus norvegicus
Last Modified: 2020-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.