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Gene: Pard3 (par-3 family cell polarity regulator) Rattus norvegicus
Symbol: Pard3
Name: par-3 family cell polarity regulator
Description: Exhibits identical protein binding activity; phosphatidylinositol phosphate binding activity; and protein phosphatase binding activity. Involved in several processes, including bicellular tight junction assembly; establishment of epithelial cell polarity; and protein targeting to membrane. Localizes to several cellular components, including the axonal growth cone; cell-cell junction; and neuronal cell body. Orthologous to human PARD3 (par-3 family cell polarity regulator); PARTICIPATES IN protein kinase C (PKC) signaling pathway; chemokine mediated signaling pathway; endocytosis pathway; INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene.
Type: protein-coding
Also known as: ASBP; ASIP; atypical PKC isotype-specific-interacting protein; atypical PKC-specific binding protein; atypical PKC-specific-binding protein; par-3 (partitioning defective 3) homolog; par-3 (partitioning defective 3) homolog (C. elegans); Par3; PARD-3; partitioning defective 3 homolog; partitioning-defective 3 homolog; partitioning-defective 3 homolog (C. elegans); three-PDZ containing protein similar to C. elegans PAR3 (partitioning defect)
Homo sapiens (human) : PARD3 (par-3 family cell polarity regulator)  HGNC  Alliance
Mus musculus (house mouse) : Pard3 (par-3 family cell polarity regulator)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Pard3 (par-3 family cell polarity regulator)
Pan paniscus (bonobo/pygmy chimpanzee) : PARD3 (par-3 family cell polarity regulator)
Canis lupus familiaris (dog) : PARD3 (par-3 family cell polarity regulator)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Pard3 (par-3 family cell polarity regulator)
Sus scrofa (pig) : PARD3 (par-3 family cell polarity regulator)
Chlorocebus sabaeus (African green monkey) : PARD3 (par-3 family cell polarity regulator)
Heterocephalus glaber (naked mole-rat) : Pard3 (par-3 family cell polarity regulator)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01960,017,746 - 60,580,628 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1960,017,746 - 60,580,651 (+)Ensembl
Rnor_5.01970,690,939 - 71,249,213 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41957,015,742 - 57,603,133 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11957,020,801 - 57,608,193 (+)NCBI
Celera1954,418,687 - 54,967,349 (+)NCBICelera
Cytogenetic Map19q12NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Pard3
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 620374
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2020-02-11
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.