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Gene: Pdp1 (pyruvate dehyrogenase phosphatase catalytic subunit 1) Rattus norvegicus
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Symbol: Pdp1
Name: pyruvate dehyrogenase phosphatase catalytic subunit 1
Description: Exhibits metal ion binding activity and phosphatase activity. Involved in protein dephosphorylation. Localizes to the mitochondrion. Human ortholog(s) of this gene implicated in obesity and pyruvate decarboxylase deficiency. Orthologous to human PDP1 (pyruvate dehyrogenase phosphatase catalytic subunit 1); PARTICIPATES IN pyruvate metabolic pathway; INTERACTS WITH (+)-schisandrin B; (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; 2,4-dinitrotoluene.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: [Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 1, mitochondrial; PDP 1; PDPC 1; Ppm2c; protein phosphatase 2C, magnesium dependent, catalytic subunit; protein phosphatase 2C, magnesium-dependent, catalytic subunit; pyruvate dehydrogenase [acetyl-transferring]-phosphatase 1, mitochondrial; pyruvate dehydrogenase phosphatase catalytic subunit 1; pyruvate dehydrogenase phosphatase isoenzyme 1; pyruvate dehydrogenase phosphatase, catalytic subunit 1
Orthologs:
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0525,577,593 - 25,584,325 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0530,284,064 - 30,290,681 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4526,234,414 - 26,240,301 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1526,234,515 - 26,241,115 (-)NCBI
Celera524,779,851 - 24,786,537 (-)NCBICelera
Cytogenetic Map5q13NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Pdp1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 620393
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.