Gene: Jup (junction plakoglobin) Rattus norvegicus
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Symbol: Jup
Name: junction plakoglobin
Description: Exhibits protein kinase binding activity and structural molecule activity; involved in cell-cell adhesion and protein heterooligomerization; localizes to several cellular components, including the apicolateral plasma membrane, cytoplasm, and cytoplasmic side of plasma membrane; colocalizes with the actin cytoskeleton; orthologous to human JUP (junction plakoglobin); PARTICIPATES IN E-cadherin signaling pathway; N-cadherin signaling pathway; acute myeloid leukemia pathway; INTERACTS WITH (RS)-amphetamine; 2,2',4,4',5,5'-hexachlorobiphenyl; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: gamma-catenin (plakoglobin)
Orthologs:
Homo sapiens (human) : JUP (junction plakoglobin)  HGNC  Alliance
Mus musculus (house mouse) : Jup (junction plakoglobin)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Jup (junction plakoglobin)
Pan paniscus (bonobo/pygmy chimpanzee) : JUP (junction plakoglobin)
Canis lupus familiaris (dog) : JUP (junction plakoglobin)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Jup (junction plakoglobin)
Sus scrofa (pig) : JUP (junction plakoglobin)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01088,280,517 - 88,307,451 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01088,073,764 - 88,100,700 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41089,307,938 - 89,335,254 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11089,322,309 - 89,349,624 (-)NCBI
Celera1084,018,429 - 84,045,045 (-)NCBICelera
Cytogenetic Map10q31NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Jup
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 620412
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.