Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: Pax4 (paired box 4) Rattus norvegicus
Analyze
Symbol: Pax4
Name: paired box 4
Description: Exhibits double-stranded DNA binding activity. Involved in several processes, including negative regulation of transcription, DNA-templated; response to cAMP; and retina development in camera-type eye. Localizes to the nucleus. Used to study type 2 diabetes mellitus. Human ortholog(s) of this gene implicated in diabetic ketoacidosis; maturity-onset diabetes of the young type 9; type 1 diabetes mellitus; and type 2 diabetes mellitus. Orthologous to human PAX4 (paired box 4); PARTICIPATES IN maturity-onset diabetes of the young pathway; INTERACTS WITH 6-propyl-2-thiouracil; ammonium chloride; bis(2-ethylhexyl) phthalate.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: paired box gene 4; paired box protein Pax-4
Orthologs:
Homo sapiens (human) : PAX4 (paired box 4)  HGNC  Alliance
Mus musculus (house mouse) : Pax4 (paired box 4)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Pax4 (paired box 4)
Pan paniscus (bonobo/pygmy chimpanzee) : PAX4 (paired box 4)
Canis lupus familiaris (dog) : PAX4 (paired box 4)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Pax4 (paired box 4)
Sus scrofa (pig) : PAX4 (paired box 4)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0455,735,640 - 55,753,461 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0455,483,073 - 55,501,087 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4455,313,500 - 55,318,995 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1455,563,656 - 55,569,152 (-)NCBI
Celera452,169,993 - 52,174,904 (-)NCBICelera
Cytogenetic Map4q22NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 5.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Pax4
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 620433
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE



NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.