Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: Gucy2d (guanylate cyclase 2D, retinal) Rattus norvegicus
Analyze
Symbol: Gucy2d
Name: guanylate cyclase 2D, retinal
Description: Exhibits guanylate cyclase activity and protein homodimerization activity. Involved in cGMP-mediated signaling. Localizes to photoreceptor outer segment membrane. Human ortholog(s) of this gene implicated in Leber congenital amaurosis 1; choroidal sclerosis; cone-rod dystrophy 6; congenital stationary night blindness; and retinitis pigmentosa. Orthologous to human GUCY2D (guanylate cyclase 2D, retinal); PARTICIPATES IN visual phototransduction pathway; purine metabolic pathway; INTERACTS WITH 6-propyl-2-thiouracil; ammonium chloride; bisphenol A.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: guanylate cyclase 2D; guanylate cyclase 2D, membrane (retina-specific); guanylate cyclase 2E; guanylyl cyclase (GC-E); guanylyl cyclase 2e; guanylyl cyclase GC-E; Gucy2e; RETGC-1; retinal guanylyl cyclase 1
Orthologs:
Homo sapiens (human) : GUCY2D (guanylate cyclase 2D, retinal)  HGNC  Alliance
Mus musculus (house mouse) : Gucy2e (guanylate cyclase 2e)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Gucy2d (guanylate cyclase 2D, retinal)
Pan paniscus (bonobo/pygmy chimpanzee) : GUCY2D (guanylate cyclase 2D, retinal)
Canis lupus familiaris (dog) : GUCY2D (guanylate cyclase 2D, retinal)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Gucy2d (guanylate cyclase 2D, retinal)
Sus scrofa (pig) : GUCY2D (guanylate cyclase 2D, retinal)
Chlorocebus sabaeus (African green monkey) : GUCY2D (guanylate cyclase 2D, retinal)
Heterocephalus glaber (naked mole-rat) : Gucy2d (guanylate cyclase 2D, retinal)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01055,835,695 - 55,851,235 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1055,835,695 - 55,851,235 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01055,578,751 - 55,594,291 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41056,012,236 - 56,027,290 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11056,025,858 - 56,040,913 (-)NCBI
Celera1053,117,455 - 53,132,510 (-)NCBICelera
Cytogenetic Map10q24NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Gucy2d
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 620438
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2020-06-09
Status: ACTIVE



NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.