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Gene: Hbp1 (HMG-box transcription factor 1) Rattus norvegicus
Symbol: Hbp1
Name: HMG-box transcription factor 1
Description: Exhibits DNA-binding transcription repressor activity, RNA polymerase II-specific and RNA polymerase II proximal promoter sequence-specific DNA binding activity. Involved in negative regulation of transcription by RNA polymerase II and positive regulation of potassium ion transport. Predicted to localize to the nuclear speck. Orthologous to human HBP1 (HMG-box transcription factor 1); INTERACTS WITH 1,2,4-trimethylbenzene; 17alpha-ethynylestradiol; 3H-1,2-dithiole-3-thione.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: high mobility group box transcription factor 1; high mobility group protein 1; HMG box transcription factor 1; HMG box-containing protein 1; HMG-box containing protein 1; Hmgb1
Homo sapiens (human) : HBP1 (HMG-box transcription factor 1)  HGNC  Alliance
Mus musculus (house mouse) : Hbp1 (high mobility group box transcription factor 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Hbp1 (HMG-box transcription factor 1)
Pan paniscus (bonobo/pygmy chimpanzee) : HBP1 (HMG-box transcription factor 1)
Canis lupus familiaris (dog) : HBP1 (HMG-box transcription factor 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Hbp1 (HMG-box transcription factor 1)
Sus scrofa (pig) : HBP1 (HMG-box transcription factor 1)
Chlorocebus sabaeus (African green monkey) : HBP1 (HMG-box transcription factor 1)
Heterocephalus glaber (naked mole-rat) : Hbp1 (HMG-box transcription factor 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.0651,231,479 - 51,257,699 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl651,231,480 - 51,257,625 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0659,902,128 - 59,929,303 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4650,201,281 - 50,227,095 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1650,204,414 - 50,230,207 (-)NCBI
Celera647,731,479 - 47,757,413 (-)NCBICelera
Cytogenetic Map6q16NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Hbp1
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 620444
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2020-03-04
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.