Gene: Erbb4 (erb-b2 receptor tyrosine kinase 4) Rattus norvegicus
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Symbol: Erbb4
Name: erb-b2 receptor tyrosine kinase 4
Description: Predicted to have several functions, including epidermal growth factor receptor binding activity, protein homodimerization activity, and transcription regulatory region DNA binding activity; involved in several processes, including animal organ development, negative regulation of muscle cell apoptotic process, and nervous system development; localizes to several cellular components, including the caveola, cytoplasm, and nucleus; used to study visual epilepsy; biomarker of congestive heart failure, median neuropathy, and radiculopathy; orthologous to human ERBB4 (erb-b2 receptor tyrosine kinase 4); PARTICIPATES IN epidermal growth factor/neuregulin signaling pathway; calcium/calcium-mediated signaling pathway; endocytosis pathway; INTERACTS WITH 17alpha-ethynylestradiol; 3-chloropropane-1,2-diol; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: c-erbB-4; proto-oncogene-like protein c-ErbB-4; receptor tyrosine kinase; receptor tyrosine-protein kinase erbB-4; v-erb-a erythroblastic leukemia viral oncogene homolog 4; v-erb-b2 avian erythroblastic leukemia viral oncogene 4
Orthologs:
Homo sapiens (human) : ERBB4 (erb-b2 receptor tyrosine kinase 4)  HGNC  Alliance
Mus musculus (house mouse) : Erbb4 (erb-b2 receptor tyrosine kinase 4)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Erbb4 (erb-b2 receptor tyrosine kinase 4)
Pan paniscus (bonobo/pygmy chimpanzee) : ERBB4 (erb-b2 receptor tyrosine kinase 4)
Canis lupus familiaris (dog) : ERBB4 (erb-b2 receptor tyrosine kinase 4)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Erbb4 (erb-b2 receptor tyrosine kinase 4)
Sus scrofa (pig) : ERBB4 (erb-b2 receptor tyrosine kinase 4)
more info ...
Allele / Splice: Erbb4Tn(sb-T2/Bart3)2.208Mcwi  
Genetic Models: F344-Erbb4Tn(sb-T2/Bart3)2.208Mcwi
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0975,021,790 - 76,178,936 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0974,804,287 - 75,310,350 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4966,843,898 - 67,967,970 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1966,990,879 - 68,114,952 (-)NCBI
Celera967,006,553 - 68,064,842 (-)NCBICelera
Cytogenetic Map9q32-q33NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
Genetic Models
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
 
More on Erbb4
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 620486
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.