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Gene: Acacb (acetyl-CoA carboxylase beta) Rattus norvegicus
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Symbol: Acacb
Name: acetyl-CoA carboxylase beta
Description: Exhibits biotin binding activity. Involved in response to drug and response to organic cyclic compound. Localizes to the mitochondrion. Used to study fatty liver disease. Orthologous to human ACACB (acetyl-CoA carboxylase beta); PARTICIPATES IN fatty acid biosynthetic pathway; insulin signaling pathway; propanoate metabolic pathway; INTERACTS WITH (+)-catechin; (+)-schisandrin B; (R)-mevalonic acid.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: Acc2; acetyl-CoA carboxylase 2; acetyl-Coenzyme A carboxylase 2; acetyl-Coenzyme A carboxylase beta
Orthologs:
Homo sapiens (human) : ACACB (acetyl-CoA carboxylase beta)  HGNC  Alliance
Mus musculus (house mouse) : Acacb (acetyl-Coenzyme A carboxylase beta)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Acacb (acetyl-CoA carboxylase beta)
Pan paniscus (bonobo/pygmy chimpanzee) : ACACB (acetyl-CoA carboxylase beta)
Canis lupus familiaris (dog) : ACACB (acetyl-CoA carboxylase beta)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Acacb (acetyl-CoA carboxylase beta)
Sus scrofa (pig) : ACACB (acetyl-CoA carboxylase beta)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01248,127,149 - 48,238,969 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1248,127,149 - 48,238,887 (-)Ensembl
Rnor_5.01249,914,427 - 50,000,957 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41243,388,679 - 43,492,993 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11243,252,066 - 43,356,381 (-)NCBI
Celera1243,976,897 - 44,062,163 (-)NCBICelera
Cytogenetic Map12q16NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Candidate Gene Status
Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Acacb
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 620500
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2019-10-16
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.