Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: Hadha (hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha) Rattus norvegicus
Analyze
Symbol: Hadha
Name: hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha
Description: Exhibits several functions, including coenzyme binding activity; hydro-lyase activity; and long-chain-3-hydroxyacyl-CoA dehydrogenase activity. Involved in fatty acid beta-oxidation and response to drug. Localizes to the mitochondrial fatty acid beta-oxidation multienzyme complex. Human ortholog(s) of this gene implicated in fatty liver disease. Orthologous to human HADHA (hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha); PARTICIPATES IN fatty acid metabolic pathway; carnitine palmitoyltransferase I deficiency pathway; ethylmalonic encephalopathy pathway; INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,4,6-trinitrotoluene.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit; hydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A hiolase/enoyl-Coenzyme A hydratase (trifunctional protein), alpha subunit; hydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A thiolase/enoyl-Coenzyme A hydratase (trifunctional protein), alpha subunit; MGC105338; monolysocardiolipin acyltransferase; RGD1560655; TP-alpha; trifunctional enzyme subunit alpha, mitochondrial
Orthologs:
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: suggests misassembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0627,589,840 - 27,628,921 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0637,400,511 - 37,439,592 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4626,173,798 - 26,191,433 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1626,176,752 - 26,194,387NCBI
Celera625,664,847 - 25,704,584 (+)NCBICelera
Cytogenetic Map6q14NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
 
More on Hadha
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 620512
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2019-07-09
Status: ACTIVE



NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.