Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: Slc6a1 (solute carrier family 6 member 1) Rattus norvegicus
Symbol: Slc6a1
Name: solute carrier family 6 member 1
Description: Exhibits gamma-aminobutyric acid:sodium symporter activity and identical protein binding activity. Involved in several processes, including gamma-aminobutyric acid import; negative regulation of GABAergic synaptic transmission; and positive regulation of gamma-aminobutyric acid secretion. Localizes to several cellular components, including GABA-ergic synapse; cell surface; and integral component of synaptic membrane. Used to study brain ischemia. Biomarker of cerebral infarction; epilepsy; temporal lobe epilepsy; and withdrawal disorder. Orthologous to human SLC6A1 (solute carrier family 6 member 1); INTERACTS WITH (+)-pilocarpine; 17alpha-ethynylestradiol; 17beta-estradiol 3-benzoate.
Type: protein-coding
Also known as: GABA transporter protein; Gabt1; GAT-1; Gat1; sodium- and chloride-dependent GABA transporter 1; solute carrier family 6 (neurotransmitter transporter), member 1; solute carrier family 6 (neurotransmitter transporter, GABA), member 1
Homo sapiens (human) : SLC6A1 (solute carrier family 6 member 1)  HGNC  Alliance
Mus musculus (house mouse) : Slc6a1 (solute carrier family 6 (neurotransmitter transporter, GABA), member 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Slc6a1 (solute carrier family 6 member 1)
Pan paniscus (bonobo/pygmy chimpanzee) : SLC6A1 (solute carrier family 6 member 1)
Canis lupus familiaris (dog) : SLC6A1 (solute carrier family 6 member 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Slc6a1 (solute carrier family 6 member 1)
Sus scrofa (pig) : SLC6A1 (solute carrier family 6 member 1)
Chlorocebus sabaeus (African green monkey) : SLC6A1 (solute carrier family 6 member 1)
Heterocephalus glaber (naked mole-rat) : Slc6a1 (solute carrier family 6 member 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.04146,258,842 - 146,292,176 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl4146,276,862 - 146,292,213 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.04209,552,452 - 209,585,794 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44150,249,867 - 150,265,186 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.14150,494,707 - 150,510,027 (+)NCBI
Celera4136,018,664 - 136,033,983 (+)NCBICelera
Cytogenetic Map4q42NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Slc6a1
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 620533
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2020-07-28
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.