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Gene: Limk1 (LIM domain kinase 1) Rattus norvegicus
Symbol: Limk1
Name: LIM domain kinase 1
CRRD ID: 62055
Description: Predicted to have heat shock protein binding activity and protein serine/threonine kinase activity. Predicted to be involved in several processes, including actin cytoskeleton organization; negative regulation of ubiquitin-protein transferase activity; and positive regulation of cellular component organization. Localizes to several cellular components, including Golgi apparatus; axonal growth cone; and perinuclear region of cytoplasm. Orthologous to human LIMK1 (LIM domain kinase 1); PARTICIPATES IN insulin responsive facilitative sugar transporter mediated glucose transport pathway; Rab family mediated signaling pathway; Fc gamma receptor mediated signaling pathway; INTERACTS WITH 2,3,7,8-Tetrachlorodibenzofuran; 3,3',4,4',5-pentachlorobiphenyl; acetamide.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: LIM motif-containing protein kinase 1; LIM-domain containing protein kinase; LIM-domain containing protein kinase 1; LIM-domain containing, protein kinase 1; LIMK-1
Homo sapiens (human) : LIMK1 (LIM domain kinase 1)  HGNC  Alliance
Mus musculus (house mouse) : Limk1 (LIM-domain containing, protein kinase)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Limk1 (LIM domain kinase 1)
Pan paniscus (bonobo/pygmy chimpanzee) : LIMK1 (LIM domain kinase 1)
Canis lupus familiaris (dog) : LIMK1 (LIM domain kinase 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Limk1 (LIM domain kinase 1)
Sus scrofa (pig) : LIMK1 (LIM domain kinase 1)
Chlorocebus sabaeus (African green monkey) : LIMK1 (LIM domain kinase 1)
Heterocephalus glaber (naked mole-rat) : Limk1 (LIM domain kinase 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01225,036,630 - 25,070,538 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1225,036,605 - 25,070,539 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01227,037,250 - 27,070,939 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41223,091,809 - 23,125,717 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11222,951,901 - 22,985,835 (+)NCBI
Celera1223,790,979 - 23,824,570 (+)NCBICelera
Cytogenetic Map12q12NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Limk1
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 62055
Created: 2001-04-11
Species: Rattus norvegicus
Last Modified: 2020-08-20
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.