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Gene: Lpar1 (lysophosphatidic acid receptor 1) Rattus norvegicus
Symbol: Lpar1
Name: lysophosphatidic acid receptor 1
CRRD ID: 620563
Description: Exhibits G-protein alpha-subunit binding activity and phospholipid binding activity. Involved in several processes, including cellular response to 1-oleoyl-sn-glycerol 3-phosphate; nervous system development; and positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway. Localizes to several cellular components, including dendrite; neuronal cell body; and plasma membrane. Predicted to colocalize with endocytic vesicle. Used to study hepatocellular carcinoma and transient cerebral ischemia. Orthologous to human LPAR1 (lysophosphatidic acid receptor 1); PARTICIPATES IN G protein mediated signaling pathway via Galphai family; G protein mediated signaling pathway via Galphaq family; INTERACTS WITH 1-naphthyl isothiocyanate; 17alpha-ethynylestradiol; 3,3',4,4',5-pentachlorobiphenyl.
Type: protein-coding
Also known as: Edg2; endothelial differentiation, lysophosphatidic acid G-protein-coupled receptor, 2; LPA receptor 1; LPA-1; lysophosphatidic acid receptor Edg-2; MGC105279
Homo sapiens (human) : LPAR1 (lysophosphatidic acid receptor 1)  HGNC  Alliance
Mus musculus (house mouse) : Lpar1 (lysophosphatidic acid receptor 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Lpar1 (lysophosphatidic acid receptor 1)
Pan paniscus (bonobo/pygmy chimpanzee) : LPAR1 (lysophosphatidic acid receptor 1)
Canis lupus familiaris (dog) : LPAR1 (lysophosphatidic acid receptor 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Lpar1 (lysophosphatidic acid receptor 1)
Sus scrofa (pig) : LPAR1 (lysophosphatidic acid receptor 1)
Chlorocebus sabaeus (African green monkey) : LPAR1 (lysophosphatidic acid receptor 1)
Heterocephalus glaber (naked mole-rat) : Lpar1 (lysophosphatidic acid receptor 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.0575,557,038 - 75,678,067 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl575,557,042 - 75,676,584 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0579,707,131 - 79,825,313 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4576,449,470 - 76,571,458 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1576,454,582 - 76,576,571 (-)NCBI
Celera572,053,065 - 72,170,436 (-)NCBICelera
Cytogenetic Map5q24NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
More on Lpar1
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 620563
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2020-08-20
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.