Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: Sh3gl3 (SH3 domain containing GRB2 like 3, endophilin A3) Rattus norvegicus
Analyze
Symbol: Sh3gl3
Name: SH3 domain containing GRB2 like 3, endophilin A3
Description: Exhibits protein C-terminus binding activity. Involved in negative regulation of clathrin-dependent endocytosis and positive regulation of neuron differentiation. Localizes to several cellular components, including the cytoplasmic vesicle; glutamatergic synapse; and postsynaptic density, intracellular component. Orthologous to human SH3GL3 (SH3 domain containing GRB2 like 3, endophilin A3); PARTICIPATES IN clathrin-dependent synaptic vesicle endocytosis; endocytosis pathway; INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; 2,6-dinitrotoluene.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: endophilin-3; endophilin-A3; SH3 domain protein 2 C1; SH3 domain protein 2C; SH3 domain-containing GRB2-like 3; SH3 domain-containing GRB2-like protein 3; SH3-domain GRB2-like 3; Sh3d2c1; SH3P13
Orthologs:
Homo sapiens (human) : SH3GL3 (SH3 domain containing GRB2 like 3, endophilin A3)  HGNC  Alliance
Mus musculus (house mouse) : Sh3gl3 (SH3-domain GRB2-like 3)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Sh3gl3 (SH3 domain containing GRB2 like 3, endophilin A3)
Pan paniscus (bonobo/pygmy chimpanzee) : SH3GL3 (SH3 domain containing GRB2 like 3, endophilin A3)
Canis lupus familiaris (dog) : SH3GL3 (SH3 domain containing GRB2 like 3, endophilin A3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Sh3gl3 (SH3 domain containing GRB2 like 3, endophilin A3)
Sus scrofa (pig) : SH3GL3 (SH3 domain containing GRB2 like 3, endophilin A3)
Chlorocebus sabaeus (green monkey) : SH3GL3 (SH3 domain containing GRB2 like 3, endophilin A3)
Heterocephalus glaber (naked mole-rat) : Sh3gl3 (SH3 domain containing GRB2 like 3, endophilin A3)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01144,069,641 - 144,200,402 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1144,069,638 - 144,200,397 (+)Ensembl
Rnor_5.01145,001,327 - 145,131,961 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41138,398,336 - 138,529,056 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11138,476,741 - 138,607,462 (+)NCBI
Celera1128,174,057 - 128,303,475 (+)NCBICelera
Cytogenetic Map1q31NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Sh3gl3
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 620578
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2019-11-27
Status: ACTIVE



NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.