Gene: Cd14 (CD14 molecule) Rattus norvegicus
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Symbol: Cd14
Name: CD14 molecule
Description: Predicted to have lipopeptide binding activity, lipopolysaccharide binding activity, and lipoteichoic acid binding activity; involved in several processes, including cellular response to lipopolysaccharide, inflammatory response, and positive regulation of cytokine secretion; localizes to the cell surface, extracellular space, and plasma membrane; used to study perinatal necrotizing enterocolitis; biomarker of Hirschsprung's disease, cholestasis, obstructive jaundice, and periodontitis; orthologous to human CD14 (CD14 molecule); PARTICIPATES IN cardiovascular system disease pathway; innate immune response pathway; Toll-like receptor signaling pathway; INTERACTS WITH (RS)-amphetamine; (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; (S)-colchicine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: CD14 antigen; monocyte differentiation antigen CD14; myeloid cell-specific leucine-rich glycoprotein
Orthologs:
Homo sapiens (human) : CD14 (CD14 molecule)  HGNC  Alliance
Mus musculus (house mouse) : Cd14 (CD14 antigen)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Cd14 (CD14 molecule)
Pan paniscus (bonobo/pygmy chimpanzee) : CD14 (CD14 molecule)
Canis lupus familiaris (dog) : CD14 (CD14 molecule)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Cd14 (CD14 molecule)
Sus scrofa (pig) : CD14 (CD14 molecule)
more info ...
Allele / Splice: Cd14em1Mcwi   Cd14em2Mcwi  
Genetic Models: SS-Cd14em2Mcwi SS-Cd14em1Mcwi
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01829,560,341 - 29,562,290 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01829,265,328 - 29,267,236 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41829,374,593 - 29,376,190 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11829,401,242 - 29,402,836 (-)NCBI
Celera1828,056,118 - 28,057,715 (-)NCBICelera
Cytogenetic Map18p11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
QTLs in Region (Rnor_6.0)
Genetic Models
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Cd14
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 620588
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.