Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: Arhgef7 (Rho guanine nucleotide exchange factor 7) Rattus norvegicus
Analyze
Symbol: Arhgef7
Name: Rho guanine nucleotide exchange factor 7
Description: Exhibits protein kinase binding activity. Contributes to Rac GTPase binding activity. Involved in actin cytoskeleton organization; astrocyte cell migration; and small GTPase mediated signal transduction. Localizes to several cellular components, including the GABA-ergic synapse; focal adhesion; and growth cone. Orthologous to human ARHGEF7 (Rho guanine nucleotide exchange factor 7); PARTICIPATES IN adenosine signaling pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; acrylamide; ammonium chloride.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: beta-Pix; P85spr; PAK-interacting exchange factor beta; Pak3bp; Rho guanine nucleotide exchange factor (GEF) 7; Rho guanine nucleotide exchange factor (GEF7)
Orthologs:
Homo sapiens (human) : ARHGEF7 (Rho guanine nucleotide exchange factor 7)  HGNC  Alliance
Mus musculus (house mouse) : Arhgef7 (Rho guanine nucleotide exchange factor (GEF7))  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Arhgef7 (Rho guanine nucleotide exchange factor 7)
Pan paniscus (bonobo/pygmy chimpanzee) : ARHGEF7 (Rho guanine nucleotide exchange factor 7)
Canis lupus familiaris (dog) : ARHGEF7 (Rho guanine nucleotide exchange factor 7)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Arhgef7 (Rho guanine nucleotide exchange factor 7)
Sus scrofa (pig) : ARHGEF7 (Rho guanine nucleotide exchange factor 7)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01683,006,732 - 83,117,065 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01682,479,277 - 82,605,606 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41682,521,224 - 82,603,338 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11682,517,165 - 82,563,059 (-)NCBI
Celera1675,472,865 - 75,551,301 (-)NCBICelera
Cytogenetic Map16q12.5NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Arhgef7
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 620624
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE



NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.