Gene: Cyp2d4 (cytochrome P450, family 2, subfamily d, polypeptide 4) Rattus norvegicus
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Symbol: Cyp2d4
Name: cytochrome P450, family 2, subfamily d, polypeptide 4
Description: Exhibits arachidonic acid monooxygenase activity; involved in several processes, including C21-steroid hormone metabolic process, carboxylic acid metabolic process, and dopamine biosynthetic process; localizes to the intracellular membrane-bounded organelle; orthologous to human CYP2D6 (cytochrome P450 family 2 subfamily D member 6); PARTICIPATES IN celecoxib pharmacodynamics pathway; celecoxib pharmacokinetics pathway; citalopram pharmacodynamics pathway; INTERACTS WITH (S)-duloxetine hydrochloride; 1-naphthyl isothiocyanate; 17alpha-ethynylestradiol.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: Cyp2d18; Cyp2d22; Cyp2d4v1; Cyp2d4v2; Cyp2d6; Cyp2d6_mapped; CYPIID18; CYPIID4; cytochrome P450 2D-29; cytochrome P450 2D-35; cytochrome P450 2D18; cytochrome P450 2D4; Cytochrome P450 subfamily IID4; cytochrome P450, family 2, subfamily d, polypeptide 22; cytochrome P450, subfamily 2D, polypeptide 6; Cytochrome P450, subfamily IID, polypeptide 6; cytochrome P450, subfamily IID, polypeptide 6 (mapped); Cytochrome P450, subfamily IID4; cytochrome P450-CMF3; cytochrome P450-DB4; debrisoquine 4-hydroxylase; P450 2D-29/2D-35; P450-CMF3; P450-DB4
Orthologs:
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.07123,599,264 - 123,608,436 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.07123,583,983 - 123,593,008 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.47120,742,273 - 120,752,274 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.17120,775,536 - 120,786,502 (-)NCBI
Celera7110,197,422 - 110,206,650 (-)NCBICelera
Cytogenetic Map7q34NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Cyp2d4
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 620640
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.