Gene: Otof (otoferlin) Rattus norvegicus
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Symbol: Otof
Name: otoferlin
Description: Predicted to have AP-2 adaptor complex binding activity and calcium ion binding activity; involved in cochlea development; localizes to several cellular components, including the apical part of cell, basal part of cell, and endoplasmic reticulum; biomarker of hypothyroidism; orthologous to human OTOF (otoferlin); PARTICIPATES IN auditory mechanotransduction pathway; INTERACTS WITH 6-propyl-2-thiouracil; ammonium chloride; bisphenol A.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: fer-1-like protein 2
Orthologs:
Homo sapiens (human) : OTOF (otoferlin)  HGNC  Alliance
Mus musculus (house mouse) : Otof (otoferlin)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Otof (otoferlin)
Pan paniscus (bonobo/pygmy chimpanzee) : OTOF (otoferlin)
Canis lupus familiaris (dog) : OTOF (otoferlin)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Otof (otoferlin)
Sus scrofa (pig) : OTOF (otoferlin)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0627,328,343 - 27,424,864 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0637,140,727 - 37,237,155 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4625,912,607 - 26,008,137 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1626,003,001 - 26,007,276 (+)NCBI
Celera625,406,310 - 25,502,501 (+)NCBICelera
Cytogenetic Map6q14NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
 
More on Otof
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 620646
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.