Gene: Espn (espin) Rattus norvegicus
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Symbol: Espn
Name: espin
Description: Exhibits SH3 domain binding activity and actin filament binding activity; predicted to be involved in several processes, including locomotory behavior, negative regulation of cytoskeleton organization, and parallel actin filament bundle assembly; localizes to several cellular components, including the brush border, cytoplasm, and filamentous actin; orthologous to human ESPN (espin); PARTICIPATES IN auditory mechanotransduction pathway; INTERACTS WITH acrylamide; ammonium chloride; bisphenol A.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: actin cytoskeletal regulatory protein; ectoplasmic specialization protein; Je; Jerker deafness locus; Jerker, deafness locus
Orthologs:
Homo sapiens (human) : ESPN (espin)  HGNC  Alliance
Mus musculus (house mouse) : Espn (espin)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Espn (espin)
Pan paniscus (bonobo/pygmy chimpanzee) : ESPN (espin)
Canis lupus familiaris (dog) : ESPN (espin)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Espn (espin)
Sus scrofa (pig) : ESPN (espin)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.05169,293,356 - 169,331,338 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.05172,851,807 - 172,885,845 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45169,349,723 - 169,382,076 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.15169,359,914 - 169,392,264 (-)NCBI
Celera5160,858,704 - 160,892,256 (-)NCBICelera
Cytogenetic Map5q36NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Espn
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 620652
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.