Gene: Rps6kb1 (ribosomal protein S6 kinase B1) Rattus norvegicus
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Symbol: Rps6kb1
Name: ribosomal protein S6 kinase B1
Description: Exhibits several functions, including ATP binding activity, PDZ domain binding activity, and identical protein binding activity; involved in several processes, including aging, cell migration, and response to peptide hormone; localizes to several cellular components, including the cell surface, cytoplasm, and nucleus; biomarker of several diseases, including autosomal dominant polycystic kidney disease, dilated cardiomyopathy, hyperinsulinism, muscular atrophy, and myocardial infarction; orthologous to human RPS6KB1 (ribosomal protein S6 kinase B1); PARTICIPATES IN mTOR signaling pathway; insulin signaling pathway; insulin-like growth factor signaling pathway; INTERACTS WITH 1-octadec-9-enoylglycero-3-phosphate; 17beta-estradiol; 17beta-hydroxy-5alpha-androstan-3-one.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: 70 kDa ribosomal protein S6 kinase 1; p70 ribosomal S6 kinase alpha; p70 S6 kinase alpha; p70 S6K-alpha; p70 S6KA; p70(S6K)-alpha; p70-S6K 1; P70S6K; P70S6K1; ribosomal protein S6 kinase beta-1; ribosomal protein S6 kinase I; ribosomal protein S6 kinase, 70kDa, polypeptide 1; ribosomal protein S6 kinase, polypeptide 1; S6 kinase; S6K; S6K-beta-1; S6K1
Orthologs:
Homo sapiens (human) : RPS6KB1 (ribosomal protein S6 kinase B1)  HGNC  Alliance
Mus musculus (house mouse) : Rps6kb1 (ribosomal protein S6 kinase, polypeptide 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Rps6kb1 (ribosomal protein S6 kinase B1)
Pan paniscus (bonobo/pygmy chimpanzee) : RPS6KB1 (ribosomal protein S6 kinase B1)
Canis lupus familiaris (dog) : RPS6KB1 (ribosomal protein S6 kinase B1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Rps6kb1 (ribosomal protein S6 kinase B1)
Sus scrofa (pig) : RPS6KB1 (ribosomal protein S6 kinase B1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01073,824,200 - 73,865,503 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01076,234,192 - 76,278,394 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41076,657,024 - 76,698,088 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11076,671,395 - 76,712,458 (-)NCBI
Celera1070,248,523 - 70,289,589 (-)NCBICelera
Cytogenetic Map10q26NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Candidate Gene Status
Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
 
More on Rps6kb1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 620683
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.