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Gene: Birc2 (baculoviral IAP repeat-containing 2) Rattus norvegicus
Symbol: Birc2
Name: baculoviral IAP repeat-containing 2
Description: Predicted to have several functions, including FBXO family protein binding activity; chaperone binding activity; and cysteine-type endopeptidase inhibitor activity involved in apoptotic process. Involved in response to cAMP; response to ethanol; and response to hypoxia. Localizes to several cellular components, including XY body; membrane raft; and nucleus. Human ortholog(s) of this gene implicated in breast cancer. Orthologous to human BIRC2 (baculoviral IAP repeat containing 2); PARTICIPATES IN FasL mediated signaling pathway; nuclear factor kappa B signaling pathway; tumor necrosis factor mediated signaling pathway; INTERACTS WITH 1,3-dinitrobenzene; 17beta-estradiol; 2,4-dinitrotoluene.
Type: protein-coding
Also known as: Api2; apoptosis inhibitor 2; baculoviral IAP repeat-containing protein 2; inhibitor of apoptosis protein; rIAP1
Homo sapiens (human) : BIRC2 (baculoviral IAP repeat containing 2)  HGNC  Alliance
Mus musculus (house mouse) : Birc2 (baculoviral IAP repeat-containing 2)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Birc2 (baculoviral IAP repeat containing 2)
Pan paniscus (bonobo/pygmy chimpanzee) : BIRC2 (baculoviral IAP repeat containing 2)
Canis lupus familiaris (dog) : BIRC2 (baculoviral IAP repeat containing 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Birc2 (baculoviral IAP repeat containing 2)
Chlorocebus sabaeus (African green monkey) : BIRC2 (baculoviral IAP repeat containing 2)
Heterocephalus glaber (naked mole-rat) : Birc2 (baculoviral IAP repeat containing 2)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.086,014,014 - 6,036,668 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl86,013,207 - 6,034,142 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.086,015,753 - 6,035,532 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.484,649,559 - 4,667,733 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.184,649,558 - 4,668,104 (-)NCBI
Celera86,528,673 - 6,546,071 (-)NCBICelera
Cytogenetic Map8q11NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Birc2
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 620690
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2020-03-04
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.