Gene: Chd8 (chromodomain helicase DNA binding protein 8) Rattus norvegicus
Symbol: Chd8
Name: chromodomain helicase DNA binding protein 8
Description: Exhibits armadillo repeat domain binding activity and beta-catenin binding activity; involved in negative regulation of canonical Wnt signaling pathway and negative regulation of transcription, DNA-templated; localizes to the nucleus and protein-containing complex; orthologous to human CHD8 (chromodomain helicase DNA binding protein 8); PARTICIPATES IN Wnt signaling pathway; INTERACTS WITH 2,4-dinitrotoluene; 2,6-dinitrotoluene; ammonium chloride.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: ATP-dependent helicase CHD8; axis duplication inhibitor; beta-catenin binding protein; CHD-8; chromodomain-helicase-DNA-binding protein 8; duplin; Loc65027
Homo sapiens (human) : CHD8 (chromodomain helicase DNA binding protein 8)  HGNC  Alliance
Mus musculus (house mouse) : Chd8 (chromodomain helicase DNA binding protein 8)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Chd8 (chromodomain helicase DNA binding protein 8)
Pan paniscus (bonobo/pygmy chimpanzee) : CHD8 (chromodomain helicase DNA binding protein 8)
Canis lupus familiaris (dog) : CHD8 (chromodomain helicase DNA binding protein 8)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Chd8 (chromodomain helicase DNA binding protein 8)
Sus scrofa (pig) : CHD8 (chromodomain helicase DNA binding protein 8)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01528,612,932 - 28,672,574 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01532,423,198 - 32,482,762 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41527,642,767 - 27,704,443 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11527,684,891 - 27,696,816 (-)NCBI
Celera1525,209,591 - 25,269,314 (-)NCBICelera
Cytogenetic Map15p14NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 5.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Chd8
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 620696
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.