Gene: Lrpap1 (LDL receptor related protein associated protein 1) Rattus norvegicus
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Symbol: Lrpap1
Name: LDL receptor related protein associated protein 1
Description: Exhibits lipase binding activity; predicted to be involved in several processes, including amyloid-beta clearance by transcytosis, negative regulation of amyloid-beta clearance, and negative regulation of cell death; localizes to the rough endoplasmic reticulum lumen and vesicle; used to study membranous glomerulonephritis; biomarker of membranous glomerulonephritis; orthologous to human LRPAP1 (LDL receptor related protein associated protein 1); PARTICIPATES IN Hedgehog signaling pathway; Reelin signaling pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3H-1,2-dithiole-3-thione; ammonium chloride.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: alpha-2-macroglobulin receptor-associated protein; alpha-2-MRAP; gp330-binding 45 kDa protein; low density lipoprotein receptor-related protein associated protein 1; low density lipoprotein receptor-related protein-associated protein 1; RAP
Orthologs:
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01480,911,281 - 80,923,290 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01481,599,969 - 81,611,978 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41481,292,661 - 81,304,670 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11481,295,093 - 81,308,456 (+)NCBI
Celera1474,577,874 - 74,589,883 (+)NCBICelera
Cytogenetic Map14q21NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
 
More on Lrpap1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 620700
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.