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Gene: Homer2 (homer scaffold protein 2) Rattus norvegicus
Symbol: Homer2
Name: homer scaffold protein 2
CRRD ID: 620705
Description: Exhibits G protein-coupled glutamate receptor binding activity; identical protein binding activity; and protein domain specific binding activity. Predicted to be involved in several processes, including behavioral response to cocaine; calcium-mediated signaling using intracellular calcium source; and regulation of signal transduction. Localizes to dendrite; neuronal cell body; and plasma membrane. Human ortholog(s) of this gene implicated in autosomal dominant nonsyndromic deafness 68. Orthologous to human HOMER2 (homer scaffold protein 2); PARTICIPATES IN glutamate signaling pathway; INTERACTS WITH 1,2,4-trimethylbenzene; 2,3,7,8-tetrachlorodibenzodioxine; alachlor.
Type: protein-coding
Also known as: cupidin; homer homolog 2; homer homolog 2 (Drosophila); homer protein homolog 2; homer scaffolding protein 2; homer, neuronal immediate early gene, 2; homer-2; VASP/Ena-related gene up-regulated during seizure and LTP 2; Vesl-2
Homo sapiens (human) : HOMER2 (homer scaffold protein 2)  HGNC  Alliance
Mus musculus (house mouse) : Homer2 (homer scaffolding protein 2)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Homer2 (homer scaffold protein 2)
Pan paniscus (bonobo/pygmy chimpanzee) : HOMER2 (homer scaffold protein 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Homer2 (homer scaffold protein 2)
Sus scrofa (pig) : HOMER2 (homer scaffold protein 2)
Chlorocebus sabaeus (African green monkey) : HOMER2 (homer scaffold protein 2)
Heterocephalus glaber (naked mole-rat) : Homer2 (homer scaffold protein 2)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: partial on reference assembly
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01143,443,300 - 143,535,579 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1143,443,300 - 143,535,583 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01144,387,025 - 144,478,034 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41137,827,128 - 137,933,089 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11137,905,533 - 138,012,215 (-)NCBI
Celera1127,618,673 - 127,711,006 (-)NCBICelera
Cytogenetic Map1q31NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Homer2
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 620705
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2020-08-20
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.