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Gene: Gap43 (growth associated protein 43) Rattus norvegicus
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Symbol: Gap43
Name: growth associated protein 43
Description: Exhibits lysophosphatidic acid binding activity; phosphatidylinositol phosphate binding activity; and phosphatidylserine binding activity. Involved in nervous system development; regulation of postsynaptic specialization assembly; and tissue regeneration. Localizes to the GABA-ergic synapse and cytoplasm. Biomarker of visual epilepsy. Orthologous to human GAP43 (growth associated protein 43); PARTICIPATES IN N-cadherin signaling pathway; INTERACTS WITH (+)-pilocarpine; (S)-amphetamine; 17alpha-ethynylestradiol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: axonal membrane protein GAP-43; Basp2; brain abundant membrane attached signal protein 2; brain abundant, membrane attached signal protein 2; growth accentuating protein 43; growth-associated protein 43; MGC156666; neuromodulin; protein F1
Orthologs:
Homo sapiens (human) : GAP43 (growth associated protein 43)  HGNC  Alliance
Mus musculus (house mouse) : Gap43 (growth associated protein 43)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Gap43 (growth associated protein 43)
Pan paniscus (bonobo/pygmy chimpanzee) : GAP43 (growth associated protein 43)
Canis lupus familiaris (dog) : GAP43 (growth associated protein 43)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Gap43 (growth associated protein 43)
Sus scrofa (pig) : GAP43 (growth associated protein 43)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01158,624,198 - 58,717,916 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01162,777,623 - 62,870,998 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41159,989,085 - 60,083,971 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11160,046,673 - 60,141,558 (+)NCBI
Celera1157,921,205 - 58,014,789 (+)NCBICelera
Cytogenetic Map11q21NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Gap43
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 62071
Created: 2001-04-11
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.