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Gene: Dhh (desert hedgehog signaling molecule) Rattus norvegicus
Symbol: Dhh
Name: desert hedgehog signaling molecule
CRRD ID: 620711
Description: Predicted to have calcium ion binding activity; patched binding activity; and zinc ion binding activity. Involved in myelination; response to estradiol; and response to estrogen. Predicted to localize to extracellular space. Human ortholog(s) of this gene implicated in 46,XY sex reversal and 46,XY sex reversal 7. Orthologous to human DHH (desert hedgehog signaling molecule); PARTICIPATES IN altered Hedgehog signaling pathway; Hedgehog signaling pathway; INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 3,3',4,4',5-pentachlorobiphenyl.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: desert hedgehog; desert hedgehog homolog (Drosophila); desert hedgehog protein
Homo sapiens (human) : DHH (desert hedgehog signaling molecule)  HGNC  Alliance
Mus musculus (house mouse) : Dhh (desert hedgehog)  MGI  Alliance
Pan paniscus (bonobo/pygmy chimpanzee) : DHH (desert hedgehog signaling molecule)
Canis lupus familiaris (dog) : DHH (desert hedgehog signaling molecule)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Dhh (desert hedgehog signaling molecule)
Sus scrofa (pig) : DHH (desert hedgehog signaling molecule)
Chlorocebus sabaeus (African green monkey) : DHH (desert hedgehog signaling molecule)
Heterocephalus glaber (naked mole-rat) : Dhh (desert hedgehog signaling molecule)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.07140,575,288 - 140,580,783 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl7140,575,288 - 140,580,783 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0X115,082,778 - 115,088,273 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.47137,666,984 - 137,672,479 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.17137,745,431 - 137,748,567 (-)NCBI
Celera7126,535,827 - 126,541,767 (-)NCBICelera
Cytogenetic Map7q36NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Dhh
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 620711
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2020-09-29
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.