Gene: Kcnma1 (potassium calcium-activated channel subfamily M alpha 1) Rattus norvegicus
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Symbol: Kcnma1
Name: potassium calcium-activated channel subfamily M alpha 1
Description: Exhibits large conductance calcium-activated potassium channel activity, ligand-gated ion channel activity involved in regulation of presynaptic membrane potential, and protein homodimerization activity; involved in several processes, including aging, negative regulation of small intestine smooth muscle contraction, and positive regulation of blood vessel diameter; localizes to several cellular components, including the dendrite, external side of plasma membrane, and glutamatergic synapse; colocalizes with the mitochondrion; orthologous to human KCNMA1 (potassium calcium-activated channel subfamily M alpha 1); INTERACTS WITH (+)-pilocarpine; (+)-Pimaric acid; (R)-noradrenaline.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: BK channel; BKCa; BKCA alpha; calcium-activated potassium channel alpha subunit; calcium-activated potassium channel subunit alpha-1; calcium-activated potassium channel, subfamily M subunit alpha-1; cbv1; k(VCA)alpha; KCa1.1; Kcnma; KCNMA1b; KCNMA1c; LOC498438; maxi K channel; maxiK; potassium channel, calcium activated large conductance subfamily M alpha, member 1; potassium large conductance calcium-activated channel, subfamily M, alpha member 1; similar to potassium large conductance calcium-activated channel, subfamily M, alpha member 1; Slo; slo homolog; slo-alpha; slo1; slowpoke homolog
Orthologs:
Allele / Splice: Kcnma1_v1   Kcnma1_v2  
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: partial on reference assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.015344,204 - 1,048,849 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.015339,100 - 1,037,105 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.415575,136 - 950,275 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.115322,288 - 950,273NCBI
Celera153,556,267 - 4,246,392 (-)NCBICelera
Cytogenetic Map15p16NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Kcnma1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 620715
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.