Gene: Slc18a3 (solute carrier family 18 member A3) Rattus norvegicus
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Symbol: Slc18a3
Name: solute carrier family 18 member A3
Description: Exhibits acetylcholine transmembrane transporter activity; involved in acetylcholine transport and neurotransmitter loading into synaptic vesicle; localizes to several cellular components, including the axon terminus, cholinergic synapse, and cytoplasm; biomarker of asthma and bladder disease; orthologous to human SLC18A3 (solute carrier family 18 member A3); PARTICIPATES IN acetylcholine signaling pathway via muscarinic acetylcholine receptor; acetylcholine signaling pathway via nicotinic acetylcholine receptor; INTERACTS WITH (S)-nicotine; 1-[(2,3,4-trimethoxyphenyl)methyl]piperazine; 4-amino-2,6-dinitrotoluene.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: rVAT; solute carrier family 18 (vesicular acetylcholine transporter), member 3; solute carrier family 18 (vesicular acetylcholine), member 3; solute carrier family 18 (vesicular monoamine) member 3; solute carrier family 18 (vesicular monoamine), member 3 ; solute carrier family 18 member 3; solute carrier family 18, member 3; VACht; vesicular acetylcholine transporter
Orthologs:
Homo sapiens (human) : SLC18A3 (solute carrier family 18 member A3)  HGNC  Alliance
Mus musculus (house mouse) : Slc18a3 (solute carrier family 18 (vesicular monoamine), member 3)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Slc18a3 (solute carrier family 18 member A3)
Pan paniscus (bonobo/pygmy chimpanzee) : SLC18A3 (solute carrier family 18 member A3)
Canis lupus familiaris (dog) : SLC18A3 (solute carrier family 18 member A3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Slc18a3 (solute carrier family 18 member A3)
Sus scrofa (pig) : SLC18A3 (solute carrier family 18 member A3)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0168,682,668 - 8,685,529 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01610,648,850 - 10,651,711 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4167,969,738 - 7,972,599 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1167,969,739 - 7,972,597 (-)NCBI
Celera167,484,278 - 7,487,139 (+)NCBICelera
Cytogenetic Map16p16NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Slc18a3
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 62072
Created: 2001-04-11
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.