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Gene: Zfp36 (zinc finger protein 36) Rattus norvegicus
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Symbol: Zfp36
Name: zinc finger protein 36
Description: Exhibits mRNA 3'-UTR binding activity. Predicted to be involved in several processes, including cellular response to growth factor stimulus; cellular response to lipid; and regulation of gene expression. Localizes to the cytoplasm and nucleus. Predicted to colocalize with the CCR4-NOT complex; Dcp1-Dcp2 complex; and RISC-loading complex. Orthologous to human ZFP36 (ZFP36 ring finger protein); INTERACTS WITH (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; 1,2,4-trimethylbenzene; 1,2-dimethylhydrazine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: mRNA decay activator protein ZFP36; Tis11; TPA-induced sequence 11; tristetraprolin; tristetraproline; TTP; zfp-36
Orthologs:
Homo sapiens (human) : ZFP36 (ZFP36 ring finger protein)  HGNC  Alliance
Mus musculus (house mouse) : Zfp36 (zinc finger protein 36)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Zfp36 (ZFP36 ring finger protein)
Pan paniscus (bonobo/pygmy chimpanzee) : ZFP36 (ZFP36 ring finger protein)
Canis lupus familiaris (dog) : ZFP36 (ZFP36 ring finger protein)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Zfp36 (ZFP36 ring finger protein)
Sus scrofa (pig) : ZFP36 (ZFP36 ring finger protein)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0185,380,088 - 85,382,565 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0186,595,418 - 86,597,898 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4183,486,643 - 83,489,123 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1183,564,759 - 83,567,219 (-)NCBI
Celera178,065,353 - 78,067,833 (-)NCBICelera
Cytogenetic Map1q21NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Zfp36
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 620722
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.