Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: P2rx4 (purinergic receptor P2X 4) Rattus norvegicus
Analyze
Symbol: P2rx4
Name: purinergic receptor P2X 4
Description: Exhibits several functions, including ATP binding activity; ligand-gated cation channel activity; and transition metal ion binding activity. Involved in several processes, including cellular response to zinc ion; neuronal action potential; and positive regulation of microglial cell migration. Localizes to several cellular components, including the dendritic spine; neuronal cell body; and postsynaptic density. Biomarker of congestive heart failure. Orthologous to human P2RX4 (purinergic receptor P2X 4); PARTICIPATES IN calcium/calcium-mediated signaling pathway; INTERACTS WITH (RS)-amphetamine; ATP; benzo[a]pyrene.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: ATP receptor; P2X purinoceptor 4; P2X4; purinergic receptor P2X ligand-gated ion channel 4; purinergic receptor P2X, ligand-gated ion channel 4
Orthologs:
Homo sapiens (human) : P2RX4 (purinergic receptor P2X 4)  HGNC  Alliance
Mus musculus (house mouse) : P2rx4 (purinergic receptor P2X, ligand-gated ion channel 4)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : P2rx4 (purinergic receptor P2X 4)
Pan paniscus (bonobo/pygmy chimpanzee) : P2RX4 (purinergic receptor P2X 4)
Canis lupus familiaris (dog) : P2RX4 (purinergic receptor P2X 4)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : P2rx4 (purinergic receptor P2X 4)
Sus scrofa (pig) : P2RX4 (purinergic receptor P2X 4)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01239,308,022 - 39,325,673 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01241,196,777 - 41,214,428 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41234,943,900 - 34,961,551 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11234,807,290 - 34,824,939 (-)NCBI
Celera1235,521,444 - 35,539,095 (-)NCBICelera
Cytogenetic Map12q16NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on P2rx4
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 62073
Created: 2001-04-11
Species: Rattus norvegicus
Last Modified: 2019-10-16
Status: ACTIVE



NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.