Gene: Ephx2 (epoxide hydrolase 2) Rattus norvegicus
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Symbol: Ephx2
Name: epoxide hydrolase 2
Description: Exhibits epoxide hydrolase activity, magnesium ion binding activity, and phosphatase activity; involved in several processes, including linoleic acid metabolic process, positive regulation of blood pressure, and prostaglandin production involved in inflammatory response; localizes to the cytosol and peroxisome; used to study cerebral infarction, hypertension, and pulmonary hypertension; orthologous to human EPHX2 (epoxide hydrolase 2); PARTICIPATES IN acetylsalicylic acid pharmacodynamics pathway; antipyrine drug pathway; arachidonic acid metabolic pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3,3',4,4',5-pentachlorobiphenyl; 3-methylcholanthrene.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: bifunctional epoxide hydrolase 2; CEH; cytosolic epoxide hydrolase; epoxide hydratase; epoxide hydrolase 2, cytoplasmic; SEH; soluble epoxide hydrolase
Orthologs:
Homo sapiens (human) : EPHX2 (epoxide hydrolase 2)  HGNC  Alliance
Mus musculus (house mouse) : Ephx2 (epoxide hydrolase 2, cytoplasmic)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ephx2 (epoxide hydrolase 2)
Pan paniscus (bonobo/pygmy chimpanzee) : EPHX2 (epoxide hydrolase 2)
Canis lupus familiaris (dog) : EPHX2 (epoxide hydrolase 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ephx2 (epoxide hydrolase 2)
Sus scrofa (pig) : EPHX2 (epoxide hydrolase 2)
more info ...
Is Marker For: Strains:   SHR  
QTLs:   Strs7  
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01542,757,241 - 42,794,211 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01548,799,823 - 48,836,848 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41545,497,660 - 45,556,101 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11545,513,439 - 45,571,881 (-)NCBI
Celera1539,961,087 - 40,000,936 (-)NCBICelera
Cytogenetic Map15p12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
Related Rat Strains
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Ephx2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 620732
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.