Gene: Ptges (prostaglandin E synthase) Rattus norvegicus
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Symbol: Ptges
Name: prostaglandin E synthase
Description: Exhibits prostaglandin-E synthase activity; involved in several processes, including acute inflammatory response, chronic inflammatory response, and prostaglandin biosynthetic process; localizes to the intracellular membrane-bounded organelle and perinuclear region of cytoplasm; biomarker of Barrett's esophagus, ischemia, papilloma, peptic esophagitis, and transitional cell carcinoma; orthologous to human PTGES (prostaglandin E synthase); PARTICIPATES IN acetylsalicylic acid pharmacodynamics pathway; antipyrine drug pathway; arachidonic acid metabolic pathway; INTERACTS WITH (RS)-amphetamine; 2,2',4,4'-Tetrabromodiphenyl ether; 2,4,6-trinitrobenzenesulfonic acid.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: MGC124930; Pges
Orthologs:
Homo sapiens (human) : PTGES (prostaglandin E synthase)  HGNC  Alliance
Mus musculus (house mouse) : Ptges (prostaglandin E synthase)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ptges (prostaglandin E synthase)
Pan paniscus (bonobo/pygmy chimpanzee) : PTGES (prostaglandin E synthase)
Canis lupus familiaris (dog) : PTGES (prostaglandin E synthase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ptges (prostaglandin E synthase)
Sus scrofa (pig) : PTGES (prostaglandin E synthase)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.039,727,408 - 9,738,752 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0315,086,726 - 15,098,070 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.439,946,194 - 9,957,538 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.139,841,561 - 9,852,906 (-)NCBI
Celera38,938,064 - 8,949,408 (-)NCBICelera
Cytogenetic Map3p12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Ptges
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 62076
Created: 2001-04-11
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.