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Gene: Ptpre (protein tyrosine phosphatase, receptor type, E) Rattus norvegicus
Symbol: Ptpre
Name: protein tyrosine phosphatase, receptor type, E
Description: Predicted to have protein homodimerization activity and protein tyrosine phosphatase activity. Involved in negative regulation of insulin receptor signaling pathway. Predicted to localize to the cytoplasm; nucleus; and plasma membrane. Orthologous to human PTPRE (protein tyrosine phosphatase receptor type E); INTERACTS WITH ammonium chloride; bisphenol A; dibutyl phthalate.
Type: protein-coding
Also known as: protein tyrosine phosphatase epsilon; protein tyrosine phosphatase epsilon-like 1; protein tyrosine phosphatase epsilon-like 2; protein tyrosine phosphatase receptor type E; protein tyrosine phosphatase, receptor type, epsilon; Protein tyrosine phosphatase, receptor type, epsilon polypeptide; protein-tyrosine phosphatase epsilon; PTPepsilon; R-PTP-epsilon; receptor-type tyrosine-protein phosphatase epsilon
Homo sapiens (human) : PTPRE (protein tyrosine phosphatase receptor type E)  HGNC  Alliance
Mus musculus (house mouse) : Ptpre (protein tyrosine phosphatase, receptor type, E)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ptpre (protein tyrosine phosphatase receptor type E)
Pan paniscus (bonobo/pygmy chimpanzee) : PTPRE (protein tyrosine phosphatase receptor type E)
Canis lupus familiaris (dog) : PTPRE (protein tyrosine phosphatase receptor type E)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ptpre (protein tyrosine phosphatase receptor type E)
Sus scrofa (pig) : PTPRE (protein tyrosine phosphatase receptor type E)
more info ...
Allele / Splice: PtpreTn(sb-T2/Bart3)236Mcwi  
Genetic Models: F344-PtpreTn(sb-T2/Bart3)236Mcwi
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01207,820,719 - 207,987,123 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1207,887,209 - 207,987,136 (+)Ensembl
Rnor_5.01214,818,446 - 214,920,034 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41195,263,489 - 195,303,249 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11195,421,407 - 195,453,236 (+)NCBI
Celera1188,164,525 - 188,204,261 (+)NCBICelera
Cytogenetic Map1q41NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Candidate Gene Status
Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
Genetic Models
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Ptpre
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 620771
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.