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Gene: Sc5d (sterol-C5-desaturase) Rattus norvegicus
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Symbol: Sc5d
Name: sterol-C5-desaturase
Description: Exhibits C-5 sterol desaturase activity. Involved in cholesterol biosynthetic process via lathosterol. Localizes to the intracellular membrane-bounded organelle. Orthologous to human SC5D (sterol-C5-desaturase); PARTICIPATES IN cholesterol biosynthetic pathway; alendronate pharmacodynamics pathway; cholesterol ester storage disease pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 2,6-dinitrotoluene.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: C-5 sterol desaturase; delta(7)-sterol 5-desaturase; delta(7)-sterol C5(6)-desaturase; lathosterol 5-desaturase; lathosterol oxidase; MGC93101; Sc5dl; sterol-C5-desaturase (ERG3 delta-5-desaturase homolog, S. cerevisiae)-like; sterol-C5-desaturase (fungal ERG3 delta-5-desaturase)-like; sterol-C5-desaturase (fungal ERG3, delta-5-desaturase) homolog; sterol-C5-desaturase (fungal ERG3, delta-5-desaturase) homolog (S. cerevisae); sterol-C5-desaturase (fungal ERG3, delta-5-desaturase)-like
Orthologs:
Homo sapiens (human) : SC5D (sterol-C5-desaturase)  HGNC  Alliance
Mus musculus (house mouse) : Sc5d (sterol-C5-desaturase)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Sc5d (sterol-C5-desaturase)
Pan paniscus (bonobo/pygmy chimpanzee) : SC5D (sterol-C5-desaturase)
Canis lupus familiaris (dog) : SC5D (sterol-C5-desaturase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Sc5d (sterol-C5-desaturase)
Sus scrofa (pig) : SC5D (sterol-C5-desaturase)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0846,525,406 - 46,537,014 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl846,525,400 - 46,537,050 (-)Ensembl
Rnor_5.0844,998,826 - 45,010,434 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4845,229,976 - 45,238,924 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1845,238,758 - 45,247,690 (-)NCBI
Celera842,225,268 - 42,234,215 (-)NCBICelera
Cytogenetic Map8q22NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Sc5d
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 620775
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.