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Gene: Gtpbp4 (GTP binding protein 4) Rattus norvegicus
Symbol: Gtpbp4
Name: GTP binding protein 4
Description: Predicted to have GTP binding activity and GTPase activity. Predicted to be involved in several processes, including negative regulation of collagen binding activity; protein stabilization; and regulation of protein modification process. Localizes to nucleus. Used to study end stage renal failure. Orthologous to human GTPBP4 (GTP binding protein 4); PARTICIPATES IN ribosome biogenesis pathway; INTERACTS WITH (+)-schisandrin B; 2,4-dinitrotoluene; 2,6-dinitrotoluene.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: chronic renal failure gene protein; Crfg; G protein-binding protein CRFG; LOC498786; LOC683324; LOC689822; nucleolar GTP-binding protein 1; RGD1563564; similar to GTP-binding protein NGB; similar to Nucleolar GTP-binding protein 1 (Chronic renal failure gene protein) (GTP-binding protein NGB)
Homo sapiens (human) : GTPBP4 (GTP binding protein 4)  HGNC  Alliance
Mus musculus (house mouse) : Gtpbp4 (GTP binding protein 4)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Gtpbp4 (GTP binding protein 4)
Pan paniscus (bonobo/pygmy chimpanzee) : GTPBP4 (GTP binding protein 4)
Canis lupus familiaris (dog) : GTPBP4 (GTP binding protein 4)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Gtpbp4 (GTP binding protein 4)
Sus scrofa (pig) : GTPBP4 (GTP binding protein 4)
Chlorocebus sabaeus (African green monkey) : GTPBP4 (GTP binding protein 4)
Heterocephalus glaber (naked mole-rat) : Gtpbp4 (GTP binding protein 4)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01763,111,086 - 63,145,618 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1763,110,254 - 63,145,577 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01759,576,852 - 59,621,031 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Rnor_5.01764,882,150 - 64,895,590 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Rnor_5.01764,910,285 - 64,916,648 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41772,100,899 - 72,120,636 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11772,111,731 - 72,131,468 (+)NCBI
Celera1759,257,948 - 59,272,929 (-)NCBICelera
Cytogenetic Map17q12.1NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Gtpbp4
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 620783
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2020-03-04
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.