Gene: Tnfsf11 (TNF superfamily member 11) Rattus norvegicus
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Symbol: Tnfsf11
Name: TNF superfamily member 11
Description: Predicted to have cytokine activity and tumor necrosis factor receptor superfamily binding activity; involved in several processes, including positive regulation of bone resorption, positive regulation of osteoclast differentiation, and response to immobilization stress; predicted to localize to the extracellular space, integral component of membrane, and plasma membrane; biomarker of myocarditis; orthologous to human TNFSF11 (TNF superfamily member 11); PARTICIPATES IN interleukin-6 signaling pathway; cytokine mediated signaling pathway; rheumatoid arthritis pathway; INTERACTS WITH (20S)-ginsenoside Rg3; (S)-nicotine; 1-naphthyl isothiocyanate.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: ODF; OPGL; osteoclast differentiation factor; osteoprotegerin ligand; RANKL; receptor activator of nuclear factor kappa B ligand; receptor activator of nuclear factor kappa-B ligand; TNF-related activation-induced cytokine; TRANCE; tumor necrosis factor (ligand) superfamily, member 11; tumor necrosis factor ligand superfamily member 11; tumor necrosis factor superfamily member 11
Orthologs:
Homo sapiens (human) : TNFSF11 (TNF superfamily member 11)  HGNC  Alliance
Mus musculus (house mouse) : Tnfsf11 (tumor necrosis factor (ligand) superfamily, member 11)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Tnfsf11 (TNF superfamily member 11)
Pan paniscus (bonobo/pygmy chimpanzee) : TNFSF11 (TNF superfamily member 11)
Canis lupus familiaris (dog) : TNFSF11 (TNF superfamily member 11)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Tnfsf11 (TNF superfamily member 11)
Sus scrofa (pig) : TNFSF11 (TNF superfamily member 11)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01560,482,527 - 60,512,704 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01565,726,538 - 65,757,935 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Rnor_5.01564,155,680 - 64,186,116 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41559,397,837 - 59,428,014 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11559,413,616 - 59,443,794 (-)NCBI
Celera1553,271,197 - 53,300,935 (-)NCBICelera
Cytogenetic Map15q11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
 
More on Tnfsf11
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 620784
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.