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Gene: Kremen1 (kringle containing transmembrane protein 1) Rattus norvegicus
Symbol: Kremen1
Name: kringle containing transmembrane protein 1
CRRD ID: 620789
Description: Predicted to be involved in several processes, including negative regulation of axon regeneration; negative regulation of canonical Wnt signaling pathway; and negative regulation of ossification. Predicted to localize to neuronal cell body. Human ortholog(s) of this gene implicated in ectodermal dysplasia 13. Orthologous to human KREMEN1 (kringle containing transmembrane protein 1); PARTICIPATES IN Wnt signaling, canonical pathway; INTERACTS WITH ammonium chloride; bisphenol A; fenvalerate.
Type: protein-coding
Also known as: dickkopf receptor; Kremen; kremen protein 1; kringle containing transmembrane protein; kringle domain-containing transmembrane protein 1; kringle-coding gene marking the eye and the nose; kringle-containing protein marking the eye and the nose
Homo sapiens (human) : KREMEN1 (kringle containing transmembrane protein 1)  HGNC  Alliance
Mus musculus (house mouse) : Kremen1 (kringle containing transmembrane protein 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Kremen1 (kringle containing transmembrane protein 1)
Pan paniscus (bonobo/pygmy chimpanzee) : KREMEN1 (kringle containing transmembrane protein 1)
Canis lupus familiaris (dog) : KREMEN1 (kringle containing transmembrane protein 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Kremen1 (kringle containing transmembrane protein 1)
Sus scrofa (pig) : KREMEN1 (kringle containing transmembrane protein 1)
Chlorocebus sabaeus (African green monkey) : KREMEN1 (kringle containing transmembrane protein 1)
Heterocephalus glaber (naked mole-rat) : Kremen1 (kringle containing transmembrane protein 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: partial on reference assembly
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01485,441,209 - 85,503,661 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1485,438,707 - 85,484,275 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01486,114,543 - 86,175,894 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41485,845,443 - 85,909,575 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11485,864,587 - 85,928,720 (-)NCBI
Celera1478,972,429 - 79,034,890 (-)NCBICelera
Cytogenetic Map14q21NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Kremen1
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 620789
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2020-08-20
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.