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Gene: Nploc4 (NPL4 homolog, ubiquitin recognition factor) Rattus norvegicus
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Symbol: Nploc4
Name: NPL4 homolog, ubiquitin recognition factor
Description: Exhibits ATPase binding activity; ubiquitin binding activity; and ubiquitin protein ligase binding activity. Contributes to K48-linked polyubiquitin modification-dependent protein binding activity and K63-linked polyubiquitin modification-dependent protein binding activity. Involved in Golgi organization. Localizes to several cellular components, including UFD1-NPL4 complex; VCP-NPL4-UFD1 AAA ATPase complex; and cytosol. Orthologous to human NPLOC4 (NPL4 homolog, ubiquitin recognition factor); PARTICIPATES IN Endoplasmic Reticulum-associated degradation pathway; INTERACTS WITH (+)-schisandrin B; 3-chloropropane-1,2-diol; acetamide.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: homolog of yeast nuclear protein localization 4; MGC124575; Npl4; nuclear protein localization 4; nuclear protein localization 4 homolog; nuclear protein localization 4 homolog (S. cerevisiae); nuclear protein localization protein 4 homolog
Orthologs:
Homo sapiens (human) : NPLOC4 (NPL4 homolog, ubiquitin recognition factor)  HGNC  Alliance
Mus musculus (house mouse) : Nploc4 (NPL4 homolog, ubiquitin recognition factor)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Nploc4 (NPL4 homolog, ubiquitin recognition factor)
Pan paniscus (bonobo/pygmy chimpanzee) : NPLOC4 (NPL4 homolog, ubiquitin recognition factor)
Canis lupus familiaris (dog) : NPLOC4 (NPL4 homolog, ubiquitin recognition factor)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Nploc4 (NPL4 homolog, ubiquitin recognition factor)
Sus scrofa (pig) : NPLOC4 (NPL4 homolog, ubiquitin recognition factor)
Chlorocebus sabaeus (African green monkey) : NPLOC4 (NPL4 homolog, ubiquitin recognition factor)
Heterocephalus glaber (naked mole-rat) : Nploc4 (NPL4 homolog, ubiquitin recognition factor)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.010109,553,518 - 109,610,087 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl10109,552,649 - 109,610,030 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.010109,148,086 - 109,198,162 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.410109,809,121 - 109,878,278 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.110109,825,236 - 109,862,213 (-)NCBI
Celera10104,200,159 - 104,255,207 (-)NCBICelera
Cytogenetic Map10q32.3NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Nploc4
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 620794
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2020-06-09
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.