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Gene: Bnip3 (BCL2 interacting protein 3) Rattus norvegicus
Symbol: Bnip3
Name: BCL2 interacting protein 3
CRRD ID: 620800
Description: Exhibits identical protein binding activity. Involved in several processes, including cardiac muscle cell apoptotic process; central nervous system development; and positive regulation of cell death. Localizes to dendrite; mitochondrion; and nucleoplasm. Used to study congestive heart failure. Biomarker of several diseases, including cerebrovascular disease (multiple); chronic obstructive pulmonary disease; end stage renal disease; obesity; and retinal detachment. Orthologous to human BNIP3 (BCL2 interacting protein 3); PARTICIPATES IN hypoxia inducible factor pathway; intrinsic apoptotic pathway; mitochondrial autophagy pathway; INTERACTS WITH (+)-pilocarpine; (+)-schisandrin B; 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: BCL2/adenovirus E1B 19 kDa protein-interacting protein 3; BCL2/adenovirus E1B 19 kDa-interacting protein 3; BCL2/adenovirus E1B 19 kDa-interacting protein 3, nuclear gene for mitochondrial product; BCL2/adenovirus E1B interacting protein 3; MGC93043
Homo sapiens (human) : BNIP3 (BCL2 interacting protein 3)  HGNC  Alliance
Mus musculus (house mouse) : Bnip3 (BCL2/adenovirus E1B interacting protein 3)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Bnip3 (BCL2 interacting protein 3)
Pan paniscus (bonobo/pygmy chimpanzee) : BNIP3 (BCL2 interacting protein 3)
Canis lupus familiaris (dog) : BNIP3 (BCL2 interacting protein 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Bnip3 (BCL2 interacting protein 3)
Sus scrofa (pig) : BNIP3 (BCL2 interacting protein 3)
Chlorocebus sabaeus (African green monkey) : BNIP3 (BCL2 interacting protein 3)
Heterocephalus glaber (naked mole-rat) : Bnip3 (BCL2 interacting protein 3)
more info ...
Related Pseudogenes: Bnip3-ps1  
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01211,248,098 - 211,265,282 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1211,248,098 - 211,265,282 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01218,174,697 - 218,191,883 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41198,683,009 - 198,700,075 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11198,833,000 - 198,850,067 (-)NCBI
Celera1191,399,941 - 191,417,104 (-)NCBICelera
Cytogenetic Map1q41NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Bnip3
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 620800
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2020-09-23
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.