Gene: Lbr (lamin B receptor) Rattus norvegicus
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Symbol: Lbr
Name: lamin B receptor
Description: Exhibits chaperone binding activity and nuclear localization sequence binding activity; involved in mitotic cell cycle; localizes to the cytoplasm and nuclear pore; orthologous to human LBR (lamin B receptor); PARTICIPATES IN cholesterol biosynthetic pathway; histone modification pathway; INTERACTS WITH (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; 3,3',4,4',5-pentachlorobiphenyl; ammonium chloride.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: 3-beta-hydroxysterol Delta (14)-reductase; C-14 sterol reductase; C14SR; delta(14)-sterol reductase; delta-14-SR; integral nuclear envelope inner membrane protein; lamin-B receptor; Nbp60; sterol C14-reductase
Orthologs:
Homo sapiens (human) : LBR (lamin B receptor)  HGNC  Alliance
Mus musculus (house mouse) : Lbr (lamin B receptor)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Lbr (lamin B receptor)
Pan paniscus (bonobo/pygmy chimpanzee) : LBR (lamin B receptor)
Canis lupus familiaris (dog) : LBR (lamin B receptor)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Lbr (lamin B receptor)
Sus scrofa (pig) : LBR (lamin B receptor)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: partial on reference assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.013100,431,390 - 100,450,209 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.013106,629,770 - 106,648,432 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41397,814,439 - 97,834,860 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11398,003,374 - 98,023,796 (-)NCBI
Celera1393,078,084 - 93,097,481 (-)NCBICelera
Cytogenetic Map13q26NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Lbr
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 620813
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.