Gene: Aifm1 (apoptosis inducing factor, mitochondria associated 1) Rattus norvegicus
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Symbol: Aifm1
Name: apoptosis inducing factor, mitochondria associated 1
Description: Predicted to have DNA binding activity, FAD binding activity, and NAD(P)H oxidase activity; involved in several processes, including cellular response to hormone stimulus, cellular response to oxygen-glucose deprivation, and cellular response to reactive oxygen species; localizes to the cytosol, mitochondrion, and nucleus; biomarker of middle cerebral artery infarction, retinal detachment, retinitis pigmentosa, and transient cerebral ischemia; orthologous to human AIFM1 (apoptosis inducing factor mitochondria associated 1); PARTICIPATES IN ceramide signaling pathway; apoptotic cell death pathway; INTERACTS WITH (+)-sesamin; (Z)-3-butylidenephthalide; 17alpha-ethynylestradiol.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: Aif; apoptosis-inducing factor 1, mitochondrial; apoptosis-inducing factor, mitochondrion-associated 1; Pdcd8; programmed cell death 8; programmed cell death 8 (apoptosis-inducing factor); programmed cell death protein 8
Orthologs:
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: partial on reference assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0X135,304,063 - 135,343,062 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0X135,375,533 - 135,414,532 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X134,868,878 - 134,908,166 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1X134,942,310 - 134,981,599 (-)NCBI
CeleraX126,598,666 - 126,637,656 (-)NCBICelera
Cytogenetic MapXq36NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Aifm1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 620817
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.