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Gene: Eif2b3 (eukaryotic translation initiation factor 2B subunit gamma) Rattus norvegicus
Symbol: Eif2b3
Name: eukaryotic translation initiation factor 2B subunit gamma
Description: Exhibits guanyl-nucleotide exchange factor activity. Predicted to contribute to translation factor activity, RNA binding. Involved in several processes, including hippocampus development; response to glucose; and response to heat. Localizes to eukaryotic translation initiation factor 2B complex. Human ortholog(s) of this gene implicated in leukoencephalopathy with vanishing white matter. Orthologous to human EIF2B3 (eukaryotic translation initiation factor 2B subunit gamma); PARTICIPATES IN translation initiation pathway; RNA transport pathway; INTERACTS WITH (+)-schisandrin B; 2,4-dinitrotoluene; 2,6-dinitrotoluene.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: eIF-2B GDP-GTP exchange factor subunit gamma; eukaryotic translation initiation factor 2B, subunit 3; eukaryotic translation initiation factor 2B, subunit 3 (gamma, 58kD); eukaryotic translation initiation factor 2B, subunit 3 gamma; translation initiation factor eIF-2B subunit gamma
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: suggests misassembly
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.05135,882,946 - 135,949,276 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5135,882,967 - 135,949,818 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.05139,677,822 - 139,744,383 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45137,323,754 - 137,398,327 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.15137,328,979 - 137,403,552 (+)NCBI
Celera5129,018,586 - 129,084,980 (+)NCBICelera
Cytogenetic Map5q36NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Eif2b3
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 620821
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2020-03-04
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.