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Gene: Polr1a (RNA polymerase I subunit A) Rattus norvegicus
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Symbol: Polr1a
Name: RNA polymerase I subunit A
Description: Contributes to DNA-directed 5'-3' RNA polymerase activity. Involved in rRNA transcription. Localizes to the RNA polymerase I complex. Human ortholog(s) of this gene implicated in acrofacial dysostosis Cincinnati type. Orthologous to human POLR1A (RNA polymerase I subunit A); PARTICIPATES IN nucleotide excision repair pathway; RNA polymerase I transcription pathway; purine metabolic pathway; INTERACTS WITH (+)-schisandrin B; (RS)-amphetamine; 2,4-dinitrotoluene.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: A194; DNA-directed RNA polymerase I A; DNA-directed RNA polymerase I largest subunit; DNA-directed RNA polymerase I subunit A; DNA-directed RNA polymerase I subunit RPA1; polymerase (RNA) I polypeptide A; polymerase (RNA) I subunit A; RNA polymerase 1-4; RNA polymerase I (194 kDa subunit); RNA polymerase I 194 kDa subunit; RNA polymerase I subunit A1; Rpa1; RPA194; Rpo1-4
Orthologs:
Homo sapiens (human) : POLR1A (RNA polymerase I subunit A)  HGNC  Alliance
Mus musculus (house mouse) : Polr1a (polymerase (RNA) I polypeptide A)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Polr1a (RNA polymerase I subunit A)
Pan paniscus (bonobo/pygmy chimpanzee) : POLR1A (RNA polymerase I subunit A)
Canis lupus familiaris (dog) : POLR1A (RNA polymerase I subunit A)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Polr1a (RNA polymerase I subunit A)
Sus scrofa (pig) : POLR1A (RNA polymerase I subunit A)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0499,822,964 - 99,903,969 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.04164,601,148 - 164,665,022 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44105,187,426 - 105,251,385 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.14105,431,906 - 105,495,866 (+)NCBI
Celera493,106,344 - 93,170,325 (+)NCBICelera
Cytogenetic Map4q31NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
 
More on Polr1a
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 620824
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.