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Gene: Akap1 (A-kinase anchoring protein 1) Rattus norvegicus
Symbol: Akap1
Name: A-kinase anchoring protein 1
CRRD ID: 620826
Description: Exhibits several functions, including enzyme binding activity; protein kinase A regulatory subunit binding activity; and tubulin binding activity. Involved in several processes, including cellular response to organonitrogen compound; negative regulation of cardiac muscle hypertrophy; and negative regulation of protein import into nucleus. Localizes to several cellular components, including lipid droplet; mitochondrial crista; and neuromuscular junction. Biomarker of brain ischemia. Orthologous to human AKAP1 (A-kinase anchoring protein 1); PARTICIPATES IN protein kinase A (PKA) signaling pathway; vascular endothelial growth factor signaling pathway; INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; 3-chloropropane-1,2-diol.
Type: protein-coding
Also known as: A kinase (PRKA) anchor protein 1; a kinase anchor protein 1, mitochondrial; A-kinase anchor protein 1, mitochondrial; A-kinase anchor protein 121 kDa; AKAP 121; Akap84; D-AKAP-1; dual specificity A-kinase-anchoring protein 1; PRKA1; protein kinase A-anchoring protein 1; S-AKAP84; spermatid A-kinase anchor protein 84
Homo sapiens (human) : AKAP1 (A-kinase anchoring protein 1)  HGNC  Alliance
Mus musculus (house mouse) : Akap1 (A kinase (PRKA) anchor protein 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Akap1 (A-kinase anchoring protein 1)
Pan paniscus (bonobo/pygmy chimpanzee) : AKAP1 (A-kinase anchoring protein 1)
Canis lupus familiaris (dog) : AKAP1 (A-kinase anchoring protein 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Akap1 (A-kinase anchoring protein 1)
Sus scrofa (pig) : AKAP1 (A-kinase anchoring protein 1)
Chlorocebus sabaeus (African green monkey) : AKAP1 (A-kinase anchoring protein 1)
Heterocephalus glaber (naked mole-rat) : Akap1 (A-kinase anchoring protein 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01076,151,013 - 76,183,987 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1076,151,038 - 76,166,276 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01073,927,523 - 73,960,524 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41077,262,592 - 77,276,832 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11077,276,968 - 77,291,202 (-)NCBI
Celera1072,528,421 - 72,542,825 (-)NCBICelera
Cytogenetic Map10q26NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Candidate Gene Status
Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Akap1
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 620826
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2020-08-20
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.