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Gene: Akap1 (A-kinase anchoring protein 1) Rattus norvegicus
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Symbol: Akap1
Name: A-kinase anchoring protein 1
Description: Exhibits several functions, including enzyme binding activity; protein kinase A regulatory subunit binding activity; and tubulin binding activity. Involved in several processes, including cellular response to organonitrogen compound; negative regulation of cardiac muscle hypertrophy; and negative regulation of protein import into nucleus. Localizes to several cellular components, including the lipid droplet; mitochondrial crista; and postsynaptic membrane. Biomarker of brain ischemia. Orthologous to human AKAP1 (A-kinase anchoring protein 1); PARTICIPATES IN protein kinase A (PKA) signaling pathway; vascular endothelial growth factor signaling pathway; INTERACTS WITH (+)-schisandrin B; (RS)-amphetamine; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: A kinase (PRKA) anchor protein 1; a kinase anchor protein 1, mitochondrial; A-kinase anchor protein 1, mitochondrial; A-kinase anchor protein 121 kDa; AKAP 121; Akap84; D-AKAP-1; dual specificity A-kinase-anchoring protein 1; PRKA1; protein kinase A-anchoring protein 1; S-AKAP84; spermatid A-kinase anchor protein 84
Orthologs:
Homo sapiens (human) : AKAP1 (A-kinase anchoring protein 1)  HGNC  Alliance
Mus musculus (house mouse) : Akap1 (A kinase (PRKA) anchor protein 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Akap1 (A-kinase anchoring protein 1)
Pan paniscus (bonobo/pygmy chimpanzee) : AKAP1 (A-kinase anchoring protein 1)
Canis lupus familiaris (dog) : AKAP1 (A-kinase anchoring protein 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Akap1 (A-kinase anchoring protein 1)
Sus scrofa (pig) : AKAP1 (A-kinase anchoring protein 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01076,151,013 - 76,183,987 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01073,927,523 - 73,960,524 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41077,262,592 - 77,276,832 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11077,276,968 - 77,291,202 (-)NCBI
Celera1072,528,421 - 72,542,825 (-)NCBICelera
Cytogenetic Map10q26NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Candidate Gene Status
Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Akap1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 620826
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.