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Gene: Dusp5 (dual specificity phosphatase 5) Rattus norvegicus
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Symbol: Dusp5
Name: dual specificity phosphatase 5
Description: Exhibits MAP kinase tyrosine/serine/threonine phosphatase activity. Involved in negative regulation of transcription, DNA-templated and negative regulation of vasoconstriction. Predicted to localize to the cytoplasm and nucleus. Orthologous to human DUSP5 (dual specificity phosphatase 5); PARTICIPATES IN mitogen activated protein kinase signaling pathway; INTERACTS WITH (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; 1,2,4-trimethylbenzene; 1,3-dinitrobenzene.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: candidate plasticity-related gene 21; Cpg21; dual specificity protein phosphatase 5; MAP-kinase phosphatase (cpg21); MAP-kinase phosphatase CPG21
Orthologs:
Homo sapiens (human) : DUSP5 (dual specificity phosphatase 5)  HGNC  Alliance
Mus musculus (house mouse) : Dusp5 (dual specificity phosphatase 5)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Dusp5 (dual specificity phosphatase 5)
Pan paniscus (bonobo/pygmy chimpanzee) : DUSP5 (dual specificity phosphatase 5)
Canis lupus familiaris (dog) : DUSP5 (dual specificity phosphatase 5)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Dusp5 (dual specificity phosphatase 5)
Sus scrofa (pig) : DUSP5 (dual specificity phosphatase 5)
more info ...
Allele / Splice: Dusp5em1Mcwi  
Genetic Models: FHH-Chr 1BN-Dusp5em1Mcwi
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: partial on reference assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01274,245,184 - 274,258,595 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01281,658,075 - 281,671,486 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41259,754,234 - 259,767,645 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11259,965,278 - 259,978,690 (+)NCBI
Celera1248,260,550 - 248,274,143 (+)NCBICelera
Cytogenetic Map1q55NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
Genetic Models
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Dusp5
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 620854
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.