Gene: Axin1 (axin 1) Rattus norvegicus
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Symbol: Axin1
Name: axin 1
Description: ENCODES a protein that exhibits armadillo repeat domain binding; beta-catenin binding; identical protein binding; INVOLVED IN negative regulation of canonical Wnt signaling pathway; positive regulation of protein kinase activity; positive regulation of ubiquitin-dependent protein catabolic process; PARTICIPATES IN altered Wnt signaling, canonical pathway; colorectal cancer pathway; N-cadherin signaling pathway; ASSOCIATED WITH Caudal Duplication Anomaly (ortholog); Colorectal Neoplasms (ortholog); hepatocellular carcinoma (ortholog); FOUND IN beta-catenin destruction complex; cytoplasmic vesicle; Golgi apparatus; INTERACTS WITH 2,4-dinitrotoluene; ammonium chloride; bisphenol A
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: Axin; axin-1; axis inhibition protein 1; GSK-3beta interacting protein rAxin; rAxin
Orthologs:
Homo sapiens (human) : AXIN1 (axin 1)  HGNC  Alliance
Mus musculus (house mouse) : Axin1 (axin 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Axin1 (axin 1)
Pan paniscus (bonobo/pygmy chimpanzee) : AXIN1 (axin 1)
Canis lupus familiaris (dog) : AXIN1 (axin 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Axin1 (axin 1)
Sus scrofa (pig) : AXIN1 (axin 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: not annotated on reference assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_5.01015,324,330 - 15,376,252 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41015,409,373 - 15,462,726 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11015,410,421 - 15,463,774 (+)NCBI
Celera1014,831,660 - 14,883,421 (+)NCBICelera
Cytogenetic Map10q12NCBI


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 5.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Axin1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 620859
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.