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Gene: Axin1 (axin 1) Rattus norvegicus
Symbol: Axin1
Name: axin 1
Description: ENCODES a protein that exhibits armadillo repeat domain binding; beta-catenin binding; identical protein binding; INVOLVED IN negative regulation of canonical Wnt signaling pathway; positive regulation of protein kinase activity; positive regulation of ubiquitin-dependent protein catabolic process; PARTICIPATES IN altered Wnt signaling, canonical pathway; colorectal cancer pathway; N-cadherin signaling pathway; ASSOCIATED WITH Caudal Duplication Anomaly (ortholog); Colorectal Neoplasms (ortholog); hepatocellular carcinoma (ortholog); FOUND IN beta-catenin destruction complex; cytoplasmic vesicle; Golgi apparatus; INTERACTS WITH 2,4-dinitrotoluene; ammonium chloride; bisphenol A
Type: protein-coding
Also known as: Axin; axin-1; axis inhibition protein 1; GSK-3beta interacting protein rAxin; rAxin
Homo sapiens (human) : AXIN1 (axin 1)  HGNC  Alliance
Mus musculus (house mouse) : Axin1 (axin 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Axin1 (axin 1)
Pan paniscus (bonobo/pygmy chimpanzee) : AXIN1 (axin 1)
Canis lupus familiaris (dog) : AXIN1 (axin 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Axin1 (axin 1)
Sus scrofa (pig) : AXIN1 (axin 1)
Chlorocebus sabaeus (African green monkey) : AXIN1 (axin 1)
Heterocephalus glaber (naked mole-rat) : Axin1 (axin 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: not annotated on reference assembly
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_5.01015,324,330 - 15,376,252 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41015,409,373 - 15,462,726 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11015,410,421 - 15,463,774 (+)NCBI
Celera1014,831,660 - 14,883,421 (+)NCBICelera
Cytogenetic Map10q12NCBI

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status



Nucleotide Sequences
Protein Sequences
Damaging Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Axin1
Alliance Gene
Ensembl Gene
JBrowse: rn5
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 620859
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2020-06-09
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.