Gene: Lif (LIF, interleukin 6 family cytokine) Rattus norvegicus
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Symbol: Lif
Name: LIF, interleukin 6 family cytokine
Description: Exhibits leukemia inhibitory factor receptor binding activity; involved in several processes, including animal organ development, negative regulation of angiogenesis, and nervous system development; localizes to the extracellular space; biomarker of brain ischemia and congestive heart failure; orthologous to human LIF (LIF interleukin 6 family cytokine); PARTICIPATES IN cytokine mediated signaling pathway; Jak-Stat signaling pathway; INTERACTS WITH (+)-pilocarpine; 1,3-dinitrobenzene; 1-naphthyl isothiocyanate.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: cholinergic neuronal differentiation factor; leukemia inhibitory factor; leukemia inhibitory factor (cholinergic differentiation factor)
Orthologs:
Homo sapiens (human) : LIF (LIF interleukin 6 family cytokine)  HGNC  Alliance
Mus musculus (house mouse) : Lif (leukemia inhibitory factor)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Lif (LIF interleukin 6 family cytokine)
Pan paniscus (bonobo/pygmy chimpanzee) : LIF (LIF interleukin 6 family cytokine)
Canis lupus familiaris (dog) : LIF (LIF interleukin 6 family cytokine)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Lif (LIF interleukin 6 family cytokine)
Sus scrofa (pig) : LIF (LIF interleukin 6 family cytokine)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01484,482,652 - 84,500,574 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01485,163,603 - 85,181,855 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41484,887,856 - 84,890,630 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11484,907,000 - 84,909,775 (+)NCBI
Celera1478,044,967 - 78,047,741 (+)NCBICelera
Cytogenetic Map14q21NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Lif
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 620865
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.