Gene: F2rl1 (F2R like trypsin receptor 1) Rattus norvegicus
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Symbol: F2rl1
Name: F2R like trypsin receptor 1
Description: Predicted to have G protein-coupled receptor activity, G-protein alpha-subunit binding activity, and G-protein beta-subunit binding activity; involved in positive regulation of blood vessel diameter and positive regulation of glomerular filtration; predicted to localize to the early endosome, integral component of plasma membrane, and pseudopodium; biomarker of lung disease; orthologous to human F2RL1 (F2R like trypsin receptor 1); PARTICIPATES IN protease mediated signaling via protease-activated receptor 2; sleeping sickness pathway; INTERACTS WITH 1-naphthyl isothiocyanate; 2,2',4,4'-Tetrabromodiphenyl ether; 3,3',4,4',5-pentachlorobiphenyl.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: coagulation factor II (thrombin) receptor-like 1; coagulation factor II receptor-like 1; Par-2; Par2; proteinase-activated receptor 2; Proteinase-activated receptor-2 G protein-coupled receptor 11; Proteinase-activated receptor-2, G protein-coupled receptor 11; thrombin receptor-like 1
Orthologs:
Homo sapiens (human) : F2RL1 (F2R like trypsin receptor 1)  HGNC  Alliance
Mus musculus (house mouse) : F2rl1 (coagulation factor II (thrombin) receptor-like 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : F2rl1 (F2R like trypsin receptor 1)
Pan paniscus (bonobo/pygmy chimpanzee) : F2RL1 (F2R like trypsin receptor 1)
Canis lupus familiaris (dog) : F2RL1 (F2R like trypsin receptor 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : F2rl1 (F2R like trypsin receptor 1)
Sus scrofa (pig) : F2RL1 (F2R like trypsin receptor 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0225,222,324 - 25,235,275 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0244,378,262 - 44,391,213 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4225,886,177 - 25,899,128 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1225,808,013 - 25,819,410 (-)NCBI
Celera222,836,384 - 22,849,335 (-)NCBICelera
Cytogenetic Map2q12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
 
More on F2rl1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 620866
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.